The second season of Prison Break, an American serial drama television series, commenced airing in the United States on August 21, 2006 on the Fox Broadcasting Company. Prison Break is produced by Adelstein-Parouse Productions, in association with Rat Entertainment, Original Film and 20th Century Fox Television. The season contains 22 episodes, and concluded on April 2, 2007. Series creator Paul Scheuring describes the second season as "The Fugitive times eight," and likens it to the "second half of The Great Escape."